ALGEBRAIC GEOMETRIC APPROACHES TO BIOLOGICAL COMPLEXITY
Postdoctoral Research Fellowship at Harvard Medical School
Application deadline: 14 December 2015.
Applications are invited to work with Professor Jeremy Gunawardena on the above project, funded by the National Science Foundation. The Gunawardena laboratory studies cellular information processing using a combination of experimental, mathematical and computational methods and offers an intellectual space between the mathematical and the biological sciences. The project is concerned with developing and exploiting new mathematical approaches, such as "polynomial invariants" (PMID 26021467) and the "linear framework" (PMID 24103070), which can rise above the molecular complexity of biological systems through time-scale separation, without resorting to numerical simulation, and thereby distill general principles. The biological focus will be on the functionality of post-translational modification switches (PMID 24634222) and the role of mechanisms in eukaryotic gene regulation which operate away from thermodynamic equilibrium (PMID 25475875). The project will continue a strong tradition of recruiting undergraduate students in the mathematical sciences for research projects. Several such students have been first authors on published papers and the Postdoctoral Research Fellow will be encouraged to work with these students to develop his/her mentoring skills. Applicants should have a PhD in one of the mathematical sciences, a good track record of creative work and a strong interest in modern biology and will need to respond with enthusiasm to the challenge of developing a new inter-disciplinary scientific area. Applications should be sent to jeremy(AT)hms(DOT)harvard(DOT)edu and should include a CV, a cover letter describing suitability for the project and contact details for up to three referees. The deadline for applications is 14 December 2015. We are an equal opportunity employer and all qualified candidates will receive consideration for the position.
Copies of the papers mentioned above can be found here.
The lab has a tradition of recruiting undergraduate students in the mathematical sciences for summer internships and rotations. Please contact us if you are interested.