Germán Enciso's Home Page

Welcome to my home page - I am a postdoctoral fellow at Harvard Medical School's Systems Biology Department under prof. Jeremy Gunawardena. My dissertation work was in mathematics, studying the impact of positive and negative feedback on the behavior of dynamical systems in an abstract context. I have applied this work to models of biochemical reactions and reaction diffusion systems, and I have done some modeling of retinal interneurons. At Jeremy's lab, I am developing generic modules for biochemical reactions in little b and I will use them to study signal transduction pathways associated with EGF receptors.

I have other interests (professional and otherwise) that I hope will eventually be represented on this site. Feel free to look around and download files at your discretion (the .pdf files are intended for your personal use only, as they are actually copyrighted material).

You can download my CV

Journal Papers

L. Ukil, G. Enciso, S. Osmani, Expulsion of the nucleolus to the cytoplasm during Aspergillus nidulans mitosis and regulation of its reassembly into G1 nuclei, in preparation

G. Bond, G. Enciso, J. Waalen, E.E. Bond, H. Robins, G. Atzmon, N. Barzilai, T. Kirchhoff, K. Offit, E. Beutler and A. Levine, The impact of a MDM2 single nucleotide polymorphism (SNP309) in human cancers and longevity, in preparation

G. Enciso, A.V. Dmitriev, D. Terman, S.C. Mangel, A mathematical model of signal propagation in the starburst amacrine cell network, preprint available upon request

G. Enciso, W. Just, Large attractors in cooperative bi-quadratic Boolean networks, Part I, Arxiv preprint

W. Just, G. Enciso, Analogues of the Hirsch and Smale theorems for cooperative Boolean and discrete systems, submitted, Arxiv preprint

G. Enciso, On a Smale theorem and nonhomogeneous equilibria in cooperative systems, to appear in the Proceedings of the American Mathematical Society ( PDF )

G. Enciso, E. Sontag, Monotone Bifurcation Graphs, to appear in the Journal of Biological Dynamics ( PDF )

G. Enciso, A dichotomy for a class of cyclic delay systems. Mathematical Biosciences 208:63-75, 2007 ( PDF ).

G. Enciso, M. W. Hirsch, H.L. Smith, Prevalent behavior of strongly order preserving semiflows, to appear in the Journal of Dynamics and Differential Equations ( PDF )

B. DasGupta, G. Enciso, E. Sontag, Y. Zhang, Algorithmic and complexity results for decompositions of biological networks into monotone subsystems, Lecture Notes in Computer Science 4007: Experimental Algorithms, pp. 253-264, Springer Verlag, 2006 ( PDF ).

G. Enciso, H. Smith, E. Sontag, Non-monotone systems decomposable into monotone systems with negative feedback, Journal of Differential Equations 224:205-227, 2006 ( PDF )

G. Enciso, E. Sontag, Global attractivity, I/O monotone small-gain theorems, and biological delay systems, Discrete and Continuous Dynamical Systems 14:549-578, 2006 ( PDF )

G. Enciso, E. Sontag, Monotone systems under positive feedback: multistability and a reduction theorem, Systems and Control Letters 51(2):185-202, 2005 ( PDF )

G. Enciso, E. Sontag, On the stability of a model of testosterone dynamics, Journal of Mathematical Biology 49:627-634, 2004 ( PDF )

X. Caicedo, G. Enciso, The Hahn Banach theorem as a choice axiom, Colombian Academy of Sciences Review XXVIII:11-20, 2004 (in Spanish) ( PDF )

Peer Reviewed Conference Papers

G. Enciso, On the asymptotic behavior of a cyclic biochemical system with delay, to appear in the Proc. of the IEEE Conf. Decision and Control, San Diego, CA, Dec. 2006 ( PDF )

B. DasGupta, G. Enciso, E. Sontag, Y. Zhang, Algorithmic and complexity results for decompositions of biological networks into monotone subsystems, Fifth International Workshop on Experimental Algorithms (2006)

G. Enciso, E. Sontag, A remark on multistability for monotone systems II, Proc. IEEE Conf. Decision and Control, Seville, Dec. 2005, IEEE Publications, pp. 2957-2962, 2005 ( PDF )

G. Enciso, E. Sontag, A remark on multistability for monotone systems, Proc. IEEE Conf. Decision and Control, Paradise Island, Bahamas, Dec. 2004, IEEE Publications, pp. 249-254, 2004 ( PDF )

Thesis Dissertation and Other Publications

G. Enciso, Monotone Input/Output Systems and Applications to Biological Systems, thesis dissertation under the direction of E. Sontag, Rutgers University, 2006 (PDF)

A. DeWitt, S. Bayram, G. Enciso, H. Fernando, J. Kao, B. Pagnoncelli, D. Schmidt, J.A.S. Hameed, Data to knowledge in pharmaceutical research, Mathematical Modeling in Industry Workshop Report, IMA, Minneapolis, 2004 ( PDF )

G. Enciso, La Fuerza de Eleccián del Teorema de Hahn-Banach, Undergraduate Thesis, Universidad de los Andes, Bogotá, 2000

Lectures Given

Poster Presentations

Selected Workshops and Conferences Attended

SIAM Conference on the Life Sciences, Raleigh, NC, July 31-August 04, 2006.

Sixth International Conference on Systems Biology (ICSB 2005), Harvard Medical School, Boston, MA, October 19-24, 2005.

Sixth SIAM Conference on Control and its Applications, New Orleans Hilton, LA, July 11-14, 2005.

43rd Conference on Decision and Control, Paradise Island, Bahamas, December 14-17, 2004.

Dynamics, Control and Computation in Biochemical Networks, Banff International Research Station, Banff, Canada, August 21-25th, 2004.

Mathematical Modeling in Industry Workshop, Institute for Mathematics and its Applications, Minneapolis, MN, August 9-18th, 2004.

Workshop on Information Processing in the Biological Organism, Sheraton Four Points, Bethesda, Maryland, November 4-5th, 2003.

Biomolecular Networks Conference, Kavli Institute for Theoretical Physics, Santa Barbara, CA, January 10-18th 2002.

Random Notes

A very entertaining and commented series of mathematical discussions has been posted by Rutgers professor Doron Zeilberger in his Opinions. Without being quite as controversial, I will be posting here a couple of (not necessarily mathematical) random drafts of my own.

  1. Noisy Restaurants and Gene Expression (02/02/2007)
  2. From Tycho Brahe to Microarrays
  3. Biology and Language
  4. Universal Mathematical Reference Online
  5. Proofreading Tips

Under Construction...

Feel free to leave feedback at german dot enciso @ gmail dot com

(Link to my old website)