21 May 2021
Jennifer Oyler-Yaniv
Department of Systems Biology
Harvard Medical School
The immune system is faced by a fundamental challenge: it must balance the competing need to detect and clear pathogens, with the equally important requirement to minimize damage to bystander host cells. First, I will summarize several of our published results demonstrating mechanisms that regulate this tradeoff based on the type of infection. I will then discuss how our past work motivates us to reimagine a central paradigm of immunology — immune privilege.