The role of genome architecture in shaping brain architecture

17 May 2024

Daniele Canzio
Weill Institute for Neuroscience
UCSF

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Abstract

My lab investigates how neurons distinguish self from non-self, a process also known as neural self-avoidance. This process is critical for the establishment of neural wiring patterns during development. We are particularly interested in the role of genome architecture and epigenetic gene silencing in the generation of the transcriptional diversity underlying the process of neural self-avoidance in the mammalian brain.

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