Effects of mutation and selection on the evolution of gene expression

23 March 2018

Patricia Wittkopp
Department of Ecology and Evolutionary Biology &
Molecular, Cellular and Developmental Biology
University of Michigan


Variation in gene expression often underlies phenotypic differences within and between species, which makes understanding how gene expression evolves a key step toward understanding the evolution of higher order phenotypes. In this talk, I will discuss how new mutations alter gene regulatory networks to produce changes in gene expression and how selection shapes the variation in gene expression introduced by new mutations to produce the patterns of regulatory variation observed in diverse taxa.

current theory lunch schedule