Curvature, signaling and stability in cells

1 May 2015

Padmini Rangamani
Department of Mechanical and Aerospace Engineering
University of California San Diego


Mathematical modeling of biochemical signaling systems has allowed us great insight into the dynamics of cellular signaling systems. In this talk, I will focus on a more recently emerging aspect of cell signaling – spatial compartmetalization. I will discuss how simple mathematical models give us insight into how cell shape governs the spatio-temporal dynamics of signaling and stability behavior. I will then discuss some ongoing work on using differential geometry to predict protein distributions given a cell shape and the role of shape in governing stability behavior.

current theory lunch schedule